First published online October 16, 2008, 10.2967/jnumed.108.053264
Clinical Correlate of Brain SPECT Perfusion Abnormalities in Fibromyalgia
Eric Guedj1, Serge Cammilleri1, Jean Niboyet2, Patricia Dupont2, Eric Vidal2, Jean-Pierre Dropinski2 and Olivier Mundler1
1 Service Central de Biophysique et de Médecine Nucléaire, AP-HM Timone, Marseille, France; and 2 Unité d'Etude et de Traitement de la Douleur, Clinique La Phocéanne, Marseille, France
……………Results: FIQ total score was positively correlated with bilateral parietal perfusion, including postcentral cortex. These clusters of correlation were included in the areas of significant hyperperfusion. FIQ total score was also negatively correlated with perfusion of a left anterior temporal cluster, included in the areas of significant hypoperfusions. No other clinical correlation was observed with regional cerebral blood flow. Conclusion: These results show that brain perfusion abnormalities in patients with fibromyalgia are correlated with the clinical severity of the disease.
Key Words: brain SPECT • voxel-based analysis • fibromyalgia • pain • disability
Messaggio modificato da vivolenta, 18 dicembre 2008 - 12:12:25